Gut Microbiota and Related Metabolites Were Disturbed in Ulcerative Colitis and Partly Restored After Mesalamine Treatment

• Main Authors: Liang Dai (Author), Yingjue Tang (Author), Wenjun Zhou (Author), Yanqi Dang (Author), Qiaoli Sun (Author), Zhipeng Tang (Author), Mingzhe Zhu (Author), Guang Ji (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mesalamine has been well used in the improvement of ulcerative colitis (UC) in clinics, however, the underlying mechanisms were not well illustrated. To explore its efficacy from the perspective of gut microbiota and related metabolites, we employed 16S rRNA sequencing and metabolomics approaches in...