Optimization of Innovative Three-Dimensionally-Structured Hybrid Vesicles to Improve the Cutaneous Delivery of Clotrimazole for the Treatment of Topical Candidiasis

• Asıl Yazarlar: Maria Letizia Manca (Yazar), Iris Usach (Yazar), José Esteban Peris (Yazar), Antonella Ibba (Yazar), Germano Orrù (Yazar), Donatella Valenti (Yazar), Elvira Escribano-Ferrer (Yazar), Juan Carmelo Gomez-Fernandez (Yazar), Francisco José Aranda (Yazar), Anna Maria Fadda (Yazar), Maria Manconi (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2019-06-01T00:00:00Z.
• Konular: article
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New three-dimensionally-structured hybrid phospholipid vesicles, able to load clotrimazole in a high amount (10 mg/mL), were obtained for the first time in this work by significantly reducing the amount of water (≤10%), which was replaced with a mixture of glycerol and ethanol (≈90%). A pre-formulat...