Excessive Reversal of Epidermal Growth Factor Receptor and Ephrin Signaling Following Tracheal Occlusion in Rabbit Model of congenital Diaphragmatic Hernia

• Main Authors: Brian M Varisco (Author), Lourenco Sbragia (Author), Jing Chen (Author), Federico Scorletti (Author), Rashika Joshi (Author), Hector R Wong (Author), Rebeca Lopes-Figueira (Author), Marc Oria (Author), Jose Peiro (Author)
• Format: Book
• Published: BMC, 2016-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Congenital diaphragmatic hernia (CDH) causes severe pulmonary hypoplasia from herniation of abdominal contents into the thorax. Tracheal occlusion (TO) for human CDH improves survival, but morbidity and mortality remain high, and we do not fully understand the cellular pathways and processe...