Antitubercular, Cytotoxicity, and Computational Target Validation of Dihydroquinazolinone Derivatives

• Main Authors: Katharigatta N. Venugopala (Author), Nizar A. Al-Shar'i (Author), Lina A. Dahabiyeh (Author), Wafa Hourani (Author), Pran Kishore Deb (Author), Melendhran Pillay (Author), Bashaer Abu-Irmaileh (Author), Yasser Bustanji (Author), Sandeep Chandrashekharappa (Author), Christophe Tratrat (Author), Mahesh Attimarad (Author), Anroop B. Nair (Author), Nagaraja Sreeharsha (Author), Pottathil Shinu (Author), Michelyne Haroun (Author), Mahmoud Kandeel (Author), Abdulmalek Ahmed Balgoname (Author), Rashmi Venugopala (Author), Mohamed A. Morsy (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of 2,3-dihydroquinazolin-4(1<i>H</i>)-one derivatives (<b>3a</b>-<b>3m</b>) was screened for in vitro whole-cell antitubercular activity against the tubercular strain H37Rv and multidrug-resistant (MDR) <i>Mycobacterium tuberculosis</i> (MTB)...