Role and Association of Inflammatory and Apoptotic Caspases in Renal Tubulointerstitial Fibrosis

• Main Authors: You Ke (Author), Hui Tang (Author), Chen Ye (Author), Chun-Tao Lei (Author), Yu-Mei Wang (Author), Hua Su (Author), Chun Zhang (Author), Hua-Jun Jiang (Author)
• Format: Book
• Published: Karger Publishers, 2016-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Caspases, an evolutionary conserved family of aspartate-specific cystein proteases, play pivotal roles in apoptotic and inflammatory signaling. Thus far, 14 mammalian caspases are identified and categorized into 3 distinct sub-types: inflammatory caspases, apoptotic initiator and ap...