Modification of sodium aescinate into a safer, more stable and effective water-soluble drug by liposome-encapsulation: an in vitro and in vivo study

• Main Authors: Sifan Huang (Author), Xinyu Wang (Author), Mengmeng Liu (Author), Zhizhe Lin (Author), Wenqian Gu (Author), Haili Zhao (Author), Yanqiu Zhang (Author), Baoyue Ding (Author), Jiyong Liu (Author), Xin Wu (Author), Wei Fan (Author), Jianming Chen (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sodium aescinate (SA) is often used for intravenous (IV) injection owing to its anti-inflammatory, anti-exudative, increasing venous tension, improving blood circulation and reducing swelling activities. However, the clinical application of SA is limited by strong irritation, short half-life and low...