Estrogen deficiency induces bone loss through the gut microbiota

• Main Authors: Zhiyuan Guan (Author), Zheng Xuanqi (Author), Junxiong Zhu (Author), Wanqiong Yuan (Author), Jialin Jia (Author), Chenggui Zhang (Author), Tiantong Sun (Author), Huijie Leng (Author), Changtao Jiang (Author), Yingsheng Xu (Author), Chunli Song (Author)
• Format: Book
• Published: Elsevier, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Postmenopausal osteoporosis is a common bone metabolic disease, and gut microbiota (GM) imbalance plays an important role in the development of metabolic bone disease. Here, we show that ovariectomized mice had high levels of lipopolysaccharide in serum and gut microbiota dysbiosis through increases...