Vitamins D3 and D2 have marked but different global effects on gene expression in a rat oligodendrocyte precursor cell line

• Hauptverfasser: Manuela Mengozzi (Verfasst von), Andrew Hesketh (Verfasst von), Giselda Bucca (Verfasst von), Pietro Ghezzi (Verfasst von), Colin P. Smith (Verfasst von)
• Format: Buch
• Veröffentlicht: BMC, 2020-04-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Background Vitamin D deficiency increases the risk of developing multiple sclerosis (MS) but it is unclear whether vitamin D supplementation improves the clinical course of MS, and there is uncertainty about the dose and form of vitamin D (D2 or D3) to be used. The mechanisms underlying the...