Hydrogel Formulations Incorporating Drug Nanocrystals Enhance the Therapeutic Effect of Rebamipide in a Hamster Model for Oral Mucositis

• मुख्य लेखकों: Noriaki Nagai (लेखक), Ryotaro Seiriki (लेखक), Saori Deguchi (लेखक), Hiroko Otake (लेखक), Noriko Hiramatsu (लेखक), Hiroshi Sasaki (लेखक), Naoki Yamamoto (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2020-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

A mouthwash formulation of rebamipide (REB) is commonly used to treat oral mucositis; however, this formulation does not provide sufficient treatment or prevention in cases of serious oral mucositis. To improve treatment, we attempted to design a hydrogel incorporating REB nanocrystals (R-NPs gel)....