Efficacy and Tolerability of a Fixed-Dose Combination of Rosuvastatin and Ezetimibe Compared with a Fixed-Dose Combination of Simvastatin and Ezetimibe in Brazilian Patients with Primary Hypercholesterolemia or Mixed Dyslipidemia: A Multicenter, Randomized Trial

• Main Authors: Antonio Carlos Amedeo Vattimo, MD, MSc (Author), Francisco Antonio Helfestein Fonseca, MD, PhD (Author), Douglas Costa Morais, BSc (Author), Larissa Fontes Generoso, PhD (Author), Renata Herrera, BSc (Author), Cristiane Moraes Barbosa, BSc (Author), Maria Cristina de Oliveira Izar, MD, PhD (Author), Rita Antonelli Cardoso, PhD (Author), Stevin Zung, MD, PhD (Author)
• Format: Book
• Published: Elsevier, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT: Background: The addition of ezetimibe to statin therapy has been reported to result in increased efficacy for reduction of LDL-C levels and achievement of lipid targets, compared with monotherapy.Objective: This study was designed to demonstrate the noninferiority of therapy with fixed-dos...