Bactofection of sequences encoding a Bax protein peptide chemosensitizes prostate cancer tumor cells

• Main Authors: Marco Antonio Hernández-Luna (Author), Ricardo Díaz de León-Ortega (Author), Daniel Dimitri Hernández-Cueto (Author), Ricardo Gaxiola-Centeno (Author), Raúl Castro-Luna (Author), Leonel Martínez-Cristóbal (Author), Sara Huerta-Yépez (Author), Rosendo Luria-Pérez (Author)
• Format: Book
• Published: Permanyer, 2016-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Tumor cell resistance to chemotherapy agents is one of the main problems in the eradication of different neoplasias. One of the mechanisms of this process is the overexpression of anti-apoptotic proteins such as Bcl-2 and Bcl-XL; blocking the activity of these proteins may contribute to...