Mechanisms of Piperacillin/Tazobactam Nephrotoxicity: Piperacillin/Tazobactam-Induced Direct Tubular Damage in Mice

• Main Authors: Jihyun Yang (Author), Yoon Sook Ko (Author), Hee Young Lee (Author), Yina Fang (Author), Se Won Oh (Author), Myung-Gyu Kim (Author), Won Yong Cho (Author), Sang-Kyung Jo (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Piperacillin/tazobactam (PT) is one of the most commonly prescribed antibiotics for critically ill patients in intensive care. PT has been reported to cause direct nephrotoxicity; however, the underlying mechanisms remain unknown. We investigated the mechanisms underlying PT nephrotoxicity using a m...