In Vitro Activity of Monofunctional Pt-II Complex Based on 8-Aminoquinoline against Human Glioblastoma

In Vitro Activity of Monofunctional Pt-II Complex Based on 8-Aminoquinoline against Human Glioblastoma

A new cationic Pt(II) complex bearing 8-aminoquinoline as chelating ligand (called Pt-8AQ) was evaluated against two human carcinomas, one mesothelioma, and three glioblastoma cell lines. The in vitro comparison to the clinically approved CisPt showed a minor activity of Pt-8AQ against carcinoma and...

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Main Authors: Valentina Coccè (Author), Isabella Rimoldi (Author), Giorgio Facchetti (Author), Emilio Ciusani (Author), Giulio Alessandri (Author), Lucia Signorini (Author), Francesca Sisto (Author), Aldo Giannì (Author), Francesca Paino (Author), Augusto Pessina (Author)
Format: Book
Published: MDPI AG, 2021-12-01T00:00:00Z.
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