Investigating the Central Nervous System Disposition of Actinomycin D: Implementation and Evaluation of Cerebral Microdialysis and Brain Tissue Measurements Supported by UPLC-MS/MS Quantification
Actinomycin D is a potent cytotoxic drug against pediatric (and other) tumors that is thought to barely cross the blood-brain barrier. To evaluate its potential applicability for the treatment of patients with central nervous system (CNS) tumors, we established a cerebral microdialysis model in free...
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Materyal Türü: | Kitap |
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MDPI AG,
2021-09-01T00:00:00Z.
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A1234.567 |
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Kopya Bilgisi 1 | Kütüphanede |