A Core Omnigenic Non-coding Trait Governing Dex-Induced Osteoporotic Effects Identified Without DEXA

• Main Authors: Li Lu (Author), Yanzhen Cai (Author), Xiaoling Luo (Author), Zhangting Wang (Author), Sin Hang Fung (Author), Huanhuan Jia (Author), Chi Lam Yu (Author), Wai Yee Chan (Author), Kai Kei Miu (Author), Wende Xiao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Iatrogenic glucocorticoid (GC)-induced osteoporosis (GIO) is an idiosyncratic form of secondary osteoporosis. Genetic predisposition among individuals may give rise to variant degree of phenotypic changes but there has yet been a documented unified pathway to explain the idiosyncrasy. In this study,...