Cathepsin B-Cleavable Polymeric Photosensitizer Prodrug for Selective Photodynamic Therapy: In Vitro Studies

• Main Authors: Manish Jain (Author), Jordan Bouilloux (Author), Ines Borrego (Author), Stéphane Cook (Author), Hubert van den Bergh (Author), Norbert Lange (Author), Georges Wagnieres (Author), Marie-Noelle Giraud (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cathepsin B is a lysosomal cysteine protease that plays an important role in cancer, atherosclerosis, and other inflammatory diseases. The suppression of cathepsin B can inhibit tumor growth. The overexpression of cathepsin B can be used for the imaging and photodynamic therapy (PDT) of cancer. PDT...