Cathepsin B-Cleavable Polymeric Photosensitizer Prodrug for Selective Photodynamic Therapy: In Vitro Studies

• Главные авторы: Manish Jain (Автор), Jordan Bouilloux (Автор), Ines Borrego (Автор), Stéphane Cook (Автор), Hubert van den Bergh (Автор), Norbert Lange (Автор), Georges Wagnieres (Автор), Marie-Noelle Giraud (Автор)
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• Опубликовано: MDPI AG, 2022-04-01T00:00:00Z.
• Предметы: article
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Cathepsin B is a lysosomal cysteine protease that plays an important role in cancer, atherosclerosis, and other inflammatory diseases. The suppression of cathepsin B can inhibit tumor growth. The overexpression of cathepsin B can be used for the imaging and photodynamic therapy (PDT) of cancer. PDT...