Phthalate-Induced Fetal Leydig Cell Dysfunction Mediates Male Reproductive Tract Anomalies

• Main Authors: Yiyan Wang (Author), Chaobo Ni (Author), Xiaoheng Li (Author), Zhenkun Lin (Author), Qiqi Zhu (Author), Linxi Li (Author), Ren-Shan Ge (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Male fetal Leydig cells in the testis secrete androgen and insulin-like 3, determining the sexual differentiation. The abnormal development of fetal Leydig cells could lead to the reduction of androgen and insulin-like 3, thus causing the male reproductive tract anomalies in male neonates, including...