Low-Concentration Methylene Blue Maintains Energy Production and Strongly Improves Survival of Leigh Syndrome French Canadian Skin Fibroblasts

Low-Concentration Methylene Blue Maintains Energy Production and Strongly Improves Survival of Leigh Syndrome French Canadian Skin Fibroblasts

Abstract - Leigh syndrome French Canadian (LSFC) is a recessive disease caused by mutations in the LRPPRC gene (leucine-rich pentatricopeptide repeat containing protein). These mutations induce a cytochrome c oxidase (COX) deficiency resulting in episodes of acute acidotic crisis that will often lea...

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Bibliographic Details
Main Authors: Jean Legault (Author), Pierre-Luc Larouche (Author), Isabelle Côté (Author), Line Bouchard (Author), André Pichette (Author), Brian H Robinson (Author), Charles Morin (Author)
Format: Book
Published: Frontiers Media S.A., 2011-12-01T00:00:00Z.
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3rd Floor Main Library

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