In Vitro Nephrotoxicity and Permeation of Vancomycin Hydrochloride Loaded Liposomes

• Main Authors: Nicole Papp (Author), Jeffin Panicker (Author), John Rubino (Author), Gwendolyn Pais (Author), Alexander Czechowicz (Author), Walter C. Prozialeck (Author), Brooke Griffin (Author), Volkmar Weissig (Author), Marc Scheetz (Author), Medha D. Joshi (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drugs can be toxic to the fetus depending on the amount that permeates across the maternal-fetal barrier. One way to limit the amount which penetrates this barrier is to increase the molecular size of the drug. In this study, we have achieved this by encapsulating our model antibiotic (vancomycin hy...