In silico screening of phytochemicals from Dissotis rotundifolia against Plasmodium falciparum Dihydrofolate Reductase

• Main Authors: Latif Adams (Author), Michael Afiadenyo (Author), Samuel Kojo Kwofie (Author), Michael D. Wilson (Author), Kwadow Asamoah Kusi (Author), Dorcas Obiri-Yeboah (Author), Siobhan Moane (Author), Michelle McKeon-Bennett (Author)
• Format: Book
• Published: Elsevier, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Malaria remains a major health concern in developing countries with high morbidity and mortality, especially in pregnant women and infants. A major obstacle to the treatment of malaria is a low effectiveness and an increase resistance of the parasite to antimalarial drugs. As a result, t...