Response of a Human Lens Epithelial Cell Line to Hyperglycemic and Oxidative Stress: The Role of Aldose Reductase

• Main Authors: Gemma Sardelli (Author), Viola Scali (Author), Giovanni Signore (Author), Francesco Balestri (Author), Mario Cappiello (Author), Umberto Mura (Author), Antonella Del Corso (Author), Roberta Moschini (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A common feature of different types of diabetes is the high blood glucose levels, which are known to induce a series of metabolic alterations, leading to damaging events in different tissues. Among these alterations, both increased polyol pathway flux and oxidative stress are considered to play rele...