Response of a Human Lens Epithelial Cell Line to Hyperglycemic and Oxidative Stress: The Role of Aldose Reductase

• المؤلفون الرئيسيون: Gemma Sardelli (مؤلف), Viola Scali (مؤلف), Giovanni Signore (مؤلف), Francesco Balestri (مؤلف), Mario Cappiello (مؤلف), Umberto Mura (مؤلف), Antonella Del Corso (مؤلف), Roberta Moschini (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2023-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

A common feature of different types of diabetes is the high blood glucose levels, which are known to induce a series of metabolic alterations, leading to damaging events in different tissues. Among these alterations, both increased polyol pathway flux and oxidative stress are considered to play rele...