CD70 and PD‐L1 (CD274) co‐expression predicts poor clinical outcomes in patients with pleural mesothelioma

• Principais autores: Shingo Inaguma (Autor), Akane Ueki (Autor), Jerzy Lasota (Autor), Masayuki Komura (Autor), Asraful Nahar Sheema (Autor), Piotr Czapiewski (Autor), Renata Langfort (Autor), Janusz Rys (Autor), Joanna Szpor (Autor), Piotr Waloszczyk (Autor), Krzysztof Okoń (Autor), Wojciech Biernat (Autor), David S Schrump (Autor), Raffit Hassan (Autor), Markku Miettinen (Autor), Satoru Takahashi (Autor)
• Formato: Livro
• Publicado em: Wiley, 2023-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Diffuse pleural mesothelioma (PM) is a highly aggressive tumour typically associated with short survival. Recently, the effectiveness of first‐line immune checkpoint inhibitors in patients with unresectable PM was reported. CD70-CD27 signalling plays a co‐stimulatory role in promoting T cel...