Ubiquitous Transgenic Overexpression of C-C Chemokine Ligand 2: A Model to Assess the Combined Effect of High Energy Intake and Continuous Low-Grade Inflammation

• Main Authors: Esther Rodríguez-Gallego (Author), Marta Riera-Borrull (Author), Anna Hernández-Aguilera (Author), Roger Mariné-Casadó (Author), Anna Rull (Author), Raúl Beltrán-Debón (Author), Fedra Luciano-Mateo (Author), Javier A. Menendez (Author), Alejandro Vazquez-Martin (Author), Juan J. Sirvent (Author), Vicente Martín-Paredero (Author), Angel L. Corbí (Author), Elena Sierra-Filardi (Author), Gerard Aragonès (Author), Anabel García-Heredia (Author), Jordi Camps (Author), Carlos Alonso-Villaverde (Author), Jorge Joven (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Excessive energy management leads to low-grade, chronic inflammation, which is a significant factor predicting noncommunicable diseases. In turn, inflammation, oxidation, and metabolism are associated with the course of these diseases; mitochondrial dysfunction seems to be at the crossroads of mutua...