Metformin modifies plasma microbial-derived extracellular vesicles in polycystic ovary syndrome with insulin resistance

• Main Authors: Liping Hu (Author), Guolin Hong (Author), Jingzhi Li (Author), Mengkun Chen (Author), Chih-Jung Chang (Author), Po-Jen Cheng (Author), Zhimei Zhang (Author), Xinli Zhang (Author), Huiping Chen (Author), Yingting Zhuang (Author), Yuqin Li (Author)
• Format: Book
• Published: BMC, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Introduction This study investigated changes in plasma microbial-derived extracellular vesicles (EVs) in patients with polycystic ovary syndrome and insulin resistance (PCOS-IR) before and after metformin treatment, and aimed to identify bacterial taxa within EVs that were biologically and...