The Combination of Amoxicillin and 1,8-Cineole Improves the Bioavailability and the Therapeutic Effect of Amoxicillin in a Rabbit Model

• Egile Nagusiak: Ahmed Amin Akhmouch (Egilea), Soukayna Hriouech (Egilea), Hanane Chefchaou (Egilea), Mariam Tanghort (Egilea), Aouatef Mzabi (Egilea), Najat Chami (Egilea), Adnane Remmal (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

In this study, the effectiveness of the combination therapy of 1,8-cineole with amoxicillin (AMX) and clavulanic acid (Clav) was investigated. For this, the pharmacokinetic behaviors of AMX in rabbits were studied after a single oral dose. The animals were divided randomly into two groups: the refer...