The Combination of Amoxicillin and 1,8-Cineole Improves the Bioavailability and the Therapeutic Effect of Amoxicillin in a Rabbit Model

• Main Authors: Ahmed Amin Akhmouch (Author), Soukayna Hriouech (Author), Hanane Chefchaou (Author), Mariam Tanghort (Author), Aouatef Mzabi (Author), Najat Chami (Author), Adnane Remmal (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, the effectiveness of the combination therapy of 1,8-cineole with amoxicillin (AMX) and clavulanic acid (Clav) was investigated. For this, the pharmacokinetic behaviors of AMX in rabbits were studied after a single oral dose. The animals were divided randomly into two groups: the refer...