Atorvastatin Improves Inflammatory Response in Atherosclerosis by Upregulating the Expression of GARP

• Main Authors: Xiaoqi Zhao (Author), Yuzhou Liu (Author), Yucheng Zhong (Author), Bo Liu (Author), Kunwu Yu (Author), Huairui Shi (Author), Ruirui Zhu (Author), Kai Meng (Author), Wei Zhang (Author), Bangwei Wu (Author), Qiutang Zeng (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Regulatory T cells play an important role in the progression of atherosclerosis. GARP is a newly biological membrane molecule existed on activated Tregs, which is related to the release of TGF-β. The antiatherosclerosis effects of statins partly depend on their multiple immune modulatory potencies....