Platelet-Derived Microparticles From Obese Individuals: Characterization of Number, Size, Proteomics, and Crosstalk With Cancer and Endothelial Cells

• Main Authors: Rosalia Grande (Author), Melania Dovizio (Author), Simone Marcone (Author), Paulina B. Szklanna (Author), Annalisa Bruno (Author), H. Alexander Ebhardt (Author), Hilary Cassidy (Author), Fionnuala Ní Áinle (Author), Anna Caprodossi (Author), Paola Lanuti (Author), Marco Marchisio (Author), Geltrude Mingrone (Author), Patricia B. Maguire (Author), Paola Patrignani (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rationale: Obesity is a risk factor for atherothrombosis and various cancers. However, the mechanisms are not yet completely clarified.Objectives: We aimed to verify whether the microparticles (MPs) released from thrombin-activated platelets differed in obese and non-obese women for number, size, an...