Beneficial Effects of Polydeoxyribonucleotide (PDRN) in an In Vitro Model of Fuchs Endothelial Corneal Dystrophy

• Main Authors: Ida Ceravolo (Author), Federica Mannino (Author), Natasha Irrera (Author), Letteria Minutoli (Author), Vincenzo Arcoraci (Author), Domenica Altavilla (Author), Gian Maria Cavallini (Author), Salvatore Guarini (Author), Francesco Squadrito (Author), Giovanni Pallio (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fuchs endothelial corneal dystrophy (FECD) is a bilateral, hereditary syndrome characterized by progressive irreversible injury in the corneal endothelium; it is the most frequent cause for corneal transplantation worldwide. Oxidative stress induces the apoptosis of corneal endothelial cells (CECs),...