Anti-p53 autoantibody as early diagnostic and prognostic marker of bronchogenic carcinoma in smokers

• Главные авторы: Mohammed B.M Sofyan (Автор), Mohammad S.A Bakheet (Автор), Mostafa M.M Alomairi (Автор), Hamada Kawshtysayed (Автор), Sameh Salahelden (Автор)
• Формат: ‌
• Опубликовано: Wolters Kluwer Medknow Publications, 2018-01-01T00:00:00Z.
• Предметы: article
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Background Mutations in the tumor protein 53 (TP53) gene can lead to expression of mutant p53 proteins that accumulate in cancer cells and can induce circulating p53 antibodies in patients with cancer. Neoplastic transformation leads to elevated plasma sialic acid concentration through shedding or s...