Preparation and In Vitro/Ex Vivo Evaluation of Buccoadhesive Discs of an Anti-Parkinson Drug: Relationship between Mucoadhesivity, Drug Release and Permeability

• Main Authors: Farnaz Monajjemzadeh (Author), Mahsa Bagheri (Author), Seyed Hassan Montazam (Author), Mitra Jelvehgari (Author)
• 格式: 圖書
• 出版: Tabriz University of Medical Sciences, 2018-03-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Background: Selegiline hydrochloride (Sel) is a drug applied for the therapy of early-step Parkinson's disease. In usual clinical doses, it is an elective irreversible MAO-B inhibitor. This study intended to formulate mucoadhesive microspheres of selegiline with the objective of improving the t...