Preparation and In Vitro/Ex Vivo Evaluation of Buccoadhesive Discs of an Anti-Parkinson Drug: Relationship between Mucoadhesivity, Drug Release and Permeability

• Hoofdauteurs: Farnaz Monajjemzadeh (Auteur), Mahsa Bagheri (Auteur), Seyed Hassan Montazam (Auteur), Mitra Jelvehgari (Auteur)
• Formaat: Boek
• Gepubliceerd in: Tabriz University of Medical Sciences, 2018-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Background: Selegiline hydrochloride (Sel) is a drug applied for the therapy of early-step Parkinson's disease. In usual clinical doses, it is an elective irreversible MAO-B inhibitor. This study intended to formulate mucoadhesive microspheres of selegiline with the objective of improving the t...