Different contribution of redox-sensitive transient receptor potential channels to acetaminophen-induced death of human hepatoma cell line.
Acetaminophen (APAP) is a safe analgesic antipyretic drug at prescribed doses. Its overdose, however, can cause life-threatening liver damage. Though involvement of oxidative stress is widely acknowledged in APAP-induced hepatocellular death, the mechanism of this increased oxidative stress and the...
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Frontiers Media S.A.,
2016-02-01T00:00:00Z.
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