Expression of FRS2 in atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma: an immunohistochemical analysis of 182 cases with genetic data

• Main Authors: Wenyi Jing (Author), Ting Lan (Author), Yan Qiu (Author), Ran Peng (Author), Yang Lu (Author), Huijiao Chen (Author), Min Chen (Author), Xin He (Author), Chen Chen (Author), Hongying Zhang (Author)
• Format: Book
• Published: BMC, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The fibroblast growth factor receptor substrate 2 (FRS2) gene is located close to MDM2 and CDK4 within the 12q13-15 chromosomal region. FRS2 gene was recently found to be consistently amplified in atypical lipomatous tumor (ALT)/well-differentiated liposarcoma (WDL) and dediffere...