Deep Tumor Penetration of Doxorubicin-Loaded Glycol Chitosan Nanoparticles Using High-Intensity Focused Ultrasound

• Päätekijät: Yongwhan Choi (Tekijä), Hyounkoo Han (Tekijä), Sangmin Jeon (Tekijä), Hong Yeol Yoon (Tekijä), Hyuncheol Kim (Tekijä), Ick Chan Kwon (Tekijä), Kwangmeyung Kim (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2020-10-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

The dense extracellular matrix (ECM) in heterogeneous tumor tissues can prevent the deep tumor penetration of drug-loaded nanoparticles, resulting in a limited therapeutic efficacy in cancer treatment. Herein, we suggest that the deep tumor penetration of doxorubicin (DOX)-loaded glycol chitosan nan...