Deep Tumor Penetration of Doxorubicin-Loaded Glycol Chitosan Nanoparticles Using High-Intensity Focused Ultrasound

• Váldodahkkit: Yongwhan Choi (Dahkki), Hyounkoo Han (Dahkki), Sangmin Jeon (Dahkki), Hong Yeol Yoon (Dahkki), Hyuncheol Kim (Dahkki), Ick Chan Kwon (Dahkki), Kwangmeyung Kim (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2020-10-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The dense extracellular matrix (ECM) in heterogeneous tumor tissues can prevent the deep tumor penetration of drug-loaded nanoparticles, resulting in a limited therapeutic efficacy in cancer treatment. Herein, we suggest that the deep tumor penetration of doxorubicin (DOX)-loaded glycol chitosan nan...