Chiral Recognition R- and RS- of New Antifungal: Complexation/Solubilization/Dissolution Thermodynamics and Permeability Assay

Novel potential antifungal of 1,2,4-triazole class have been synthesized as pure enantiomer (R-98) and racemic (RS-186). The effect of 2-hydroxypropyl-β-cyclodextrin (<i>CD</i>) on the solubility and permeability of RS-186 and R-98 in terms of chiral recognition was investigated. Phase s...

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Main Authors: Tatyana V. Volkova (Author), Olga R. Simonova (Author), Igor B. Levshin (Author), German L. Perlovich (Author)
Format: Book
Published: MDPI AG, 2022-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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