Functional Analysis of TRPA1, TRPM3, and TRPV1 Channels in Human Dermal Arteries and Their Role in Vascular Modulation

• Main Authors: Eduardo Rivera-Mancilla (Author), Linda Al-Hassany (Author), Heleen Marynissen (Author), Dorien Bamps (Author), Ingrid M. Garrelds (Author), Jérôme Cornette (Author), A. H. Jan Danser (Author), Carlos M. Villalón (Author), Jan N. de Hoon (Author), Antoinette MaassenVanDenBrink (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Transient receptor potential (TRP) channels are pivotal in modulating vascular functions. In fact, topical application of cinnamaldehyde or capsaicin (TRPA1 and TRPV1 channel agonists, respectively) induces "local" changes in blood flow by releasing vasodilator neuropeptides. We investigat...