Enhancing the dissolution rate of mefenamic acid with solid dispersion system using avicel PH-101

• मुख्य लेखकों: Widyasari Putranti (लेखक), Lina Widiyastuti (लेखक), Fitri Ulfani (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Universitas Ahmad Dahlan, 2019-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Mefenamic acid, based on the Biopharmaceutics Classification System (BCS), is a class II drug that has high permeability but low water solubility. To improve its intrinsic dissolution rate, it is usually combined with a hydrophilic and porous drug carrier like Avicel to create a solid dispersion. Th...