Generation of Hepatocytes and Nonparenchymal Cell Codifferentiation System from Human-Induced Pluripotent Stem Cells

• Main Authors: Ying Shi (Author), Jiali Deng (Author), Xiaopu Sang (Author), Yihang Wang (Author), Fei He (Author), Xiaoni Chen (Author), Anlong Xu (Author), Fenfang Wu (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To date, hepatocytes derived from human-induced pluripotent stem cells (hiPSC) provide a potentially unlimited resource for clinical application and drug development. However, most hiPSC-derived hepatocyte-like cells initiated differentiation from highly purified definitive endoderm, which are insuf...