Benzene Derivatives from Ink Lead to False Positive Results in Neonatal Hyperphenylalaninemia Screening with Ninhydrin Fluorometric Method

• Main Authors: Shuren Feng (Author), Joanne Mei (Author), Lu Yang (Author), Ping Luo (Author), Xiaonan Wang (Author), Yuan Wang (Author), Jingyi Yao (Author), Lan Cui (Author), Lei Pan (Author), Zefang Wang (Author), Li Xin (Author)
• Format: Book
• Published: MDPI AG, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ninhydrin-based fluorometric quantification of phenylalanine is one of the most widely used methods for hyperphenylalaninemia (HPA) screening in neonates due to its high sensitivity, high accuracy, and low cost. Here we report an increase of false positive cases in neonatal HPA screening with this m...