S-thanatin functionalized liposome potentially targeting on Klebsiella pneumoniae and its application in sepsis mouse model

• Main Authors: Xiaobo eFan (Author), Juxiang eFan (Author), Xiyong eWang (Author), Pengpeng eWu (Author), Guoqiu eWu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

S-thanatin (Ts) was a short antimicrobial peptide with selective antibacterial activity. In this study, we aimed to design a drug carrier with specific bacterial targeting potential. The positively charged Ts was modified onto the liposome surface by linking Ts to the constituent lipids via a PEG li...