Hospital Production of Sterile 2% Propofol Nanoemulsion: Proof of Concept

• Main Authors: Amélie Cèbe (Author), Bérangère Dessane (Author), Pauline Gohier (Author), Jean-Marc Bernadou (Author), Arnaud Venet (Author), Fabien Xuereb (Author), Sylvie Crauste-Manciet (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the context of essential drug shortages, this article reports a proof of concept for the hospital preparation of a 2% propofol injectable nanoemulsion. Two processes for propofol were assessed: mixing propofol with the commercial Intralipid^® 20% emulsion and a "de novo...