Transcutaneous immunization with a highly active form of XCL1 as a vaccine adjuvant using a hydrophilic gel patch elicits long-term CD8+ T cell responses

Transcutaneous immunization with a highly active form of XCL1 as a vaccine adjuvant using a hydrophilic gel patch elicits long-term CD8+ T cell responses

Memory CD8+ cytotoxic T-lymphocytes (CTLs) play a key role in protective immunity against infection and cancer. However, the induction of memory CTLs with currently available vaccines remains difficult. The chemokine receptor XCR1 is predominantly expressed on CD103+ cross-presenting dendritic cells...

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Main Authors: Momo Kamei (Author), Kazuhiko Matsuo (Author), Haruka Imanishi (Author), Yuta Hara (Author), Ying-Shu Quen (Author), Fumio Kamiyama (Author), Naoki Oiso (Author), Akira Kawada (Author), Naoki Okada (Author), Takashi Nakayama (Author)
Format: Book
Published: Elsevier, 2020-07-01T00:00:00Z.
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