Intracellular and Extracellular Lipopolysaccharide Signaling in Sepsis: Avenues for Novel Therapeutic Strategies

• Главные авторы: Ramy S. Gabarin (Автор), Manshu Li (Автор), Paige A. Zimmel (Автор), John C. Marshall (Автор), Yimin Li (Автор), Haibo Zhang (Автор)
• Формат: ‌
• Опубликовано: Karger Publishers, 2021-05-01T00:00:00Z.
• Предметы: article
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Sepsis is defined as organ dysfunction due to a dysregulated systemic host response to infection. During gram-negative bacterial infection and other acute illness such as absorption from the gut infection, lipopolysaccharide (LPS) is a major mediator in sepsis. LPS is able to trigger inflammation th...