Insulin Resistance: A Proinflammatory State Mediated by Lipid-Induced Signaling Dysfunction and Involved in Atherosclerotic Plaque Instability

• Hauptverfasser: Fabrizio Montecucco (Verfasst von), Sabine Steffens (Verfasst von), François Mach (Verfasst von)
• Format: Buch
• Veröffentlicht: Hindawi Limited, 2008-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

The dysregulation of the insulin-glucose axis represents the crucial event in insulin resistance syndrome. Insulin resistance increases atherogenesis and atherosclerotic plaque instability by inducing proinflammatory activities on vascular and immune cells. This condition characterizes several disea...