Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity

• Main Authors: Mincheol Kwon (Author), Sung-Kyun Ko (Author), Mina Jang (Author), Gun-Hee Kim (Author), In-Ja Ryoo (Author), Sangkeun Son (Author), Hyung Won Ryu (Author), Sei-Ryang Oh (Author), Won-Kyu Lee (Author), Bo Yeon Kim (Author), Jae-Hyuk Jang (Author), Jong Seog Ahn (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Indoleamine 2,3-dioxygenase 1 (IDO1), a tryptophan catabolising enzyme, is known as a tumour cell survival factor that causes immune escape in several types of cancer. Flavonoids of Sophora flavescens have a variety of biological benefits for humans; however, cancer immunotherapy effect has not been...