Pharmacological Topics of Bone Metabolism: A Novel Bisphosphonate for the Treatment of Periodontitis

• Main Authors: Hisashi Shinoda (Author), Sadaaki Takeyama (Author), Keiko Suzuki (Author), Shinobu Murakami (Author), Shoji Yamada (Author)
• Format: Book
• Published: Elsevier, 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

It has been reported that the pharmacological characteristics of bisphosphonates vary depending on the side chain attached to the carbon atom of the P-C-P bond. TRK-530 is a novel synthetic bisphosphonate with an anti-oxidant methylthio-phenylthio side chain. This compound has been suggested to have...