Effect of teriparatide on ligamentum flavum mesenchymal stem cells isolated from patients with ossification of the posterior longitudinal ligament

• Main Authors: Ryo Araki (Author), Toru Asari (Author), Hitoshi Kudo (Author), Eiji Sasaki (Author), Ryota Yamauchi (Author), Xizhe Liu (Author), Kanichiro Wada (Author), Gentaro Kumagai (Author), Ayako Sasaki (Author), Ken-Ichi Furukawa (Author), Yasuyuki Ishibashi (Author)
• Format: Book
• Published: Elsevier, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ossification of the posterior longitudinal ligament (OPLL) within the spinal canal sometimes leads to severe myelopathy. Teriparatide (TPD) is a recombinant human parathyroid hormone (PTH) (1-34), which promotes osteogenesis of mesenchymal stem cells (MSCs) via PTH 1 receptor (PTH1R). Although ligam...