The Effect of Necrosis Inhibitor on Dextran Sulfate Sodium Induced Chronic Colitis Model in Mice

• Main Authors: Dongwoo Kim (Author), Ja Seol Koo (Author), Soon Ha Kim (Author), Yeong Seo Park (Author), Jung Wan Choe (Author), Seung Young Kim (Author), Jong Jin Hyun (Author), Sung Woo Jung (Author), Young Kul Jung (Author), Hyung Joon Yim (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Uncontrolled chronic inflammation and necrosis is characteristic of inflammatory bowel disease (IBD). This study aimed to investigate the effect of necrosis inhibitor (NI, NecroX-7) on a dextran sulfate sodium (DSS) induced chronic colitis model of mice. DSS was administered on days 1-5, and the NI...