The in vitro equivalence study of polymorph-modified glimepiride tablets compared to Amaryl®

• Main Authors: Fitrianti Darusman (Author), Taofik Rusdiana (Author), Iyan Sopyan (Author), Ratih Aryani (Author), Gita Cahya Eka Darma (Author)
• Format: Book
• Published: Pensoft Publishers, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glimepiride (GMP) is an oral antidiabetic drug classified as BCS class II, demonstrating extremely limited solubility, with a solubility level below 0.00384 mg/mL. Some generic drug manufacturers producing GMP (copy product) tablets encountered bioavailability issues due to poor dissolution, which d...