The in vitro equivalence study of polymorph-modified glimepiride tablets compared to Amaryl®

• Hlavní autoři: Fitrianti Darusman (Autor), Taofik Rusdiana (Autor), Iyan Sopyan (Autor), Ratih Aryani (Autor), Gita Cahya Eka Darma (Autor)
• Médium: Kniha
• Vydáno: Pensoft Publishers, 2023-10-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Glimepiride (GMP) is an oral antidiabetic drug classified as BCS class II, demonstrating extremely limited solubility, with a solubility level below 0.00384 mg/mL. Some generic drug manufacturers producing GMP (copy product) tablets encountered bioavailability issues due to poor dissolution, which d...