Antimetastatic Activity of Apoptolidin A by Upregulation of N-Myc Downstream-Regulated Gene 1 Expression in Human Colorectal Cancer Cells

• Main Authors: Kay Zin Kyaw (Author), Jiyoon Park (Author), Seung Ho Oh (Author), Ji Yun Lee (Author), Eun Seo Bae (Author), Hyen Joo Park (Author), Dong-Chan Oh (Author), Sang Kook Lee (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Colorectal cancer (CRC) is one of the most prevalent tumors with high metastatic potential; consequently, finding new drug candidates that suppress tumor metastasis is essential. Apoptolidin A is a macrocyclic lactone produced by <i>Amycolatopsis</i> sp. DW02G. It exhibits significant cy...