Oral Vaccination with Attenuated Salmonella typhimurium-Delivered TsPmy DNA Vaccine Elicits Protective Immunity against Trichinella spiralis in BALB/c Mice.

• Κύριοι συγγραφείς: Lei Wang (Συγγραφέας), Xiaohuan Wang (Συγγραφέας), Kuo Bi (Συγγραφέας), Ximeng Sun (Συγγραφέας), Jing Yang (Συγγραφέας), Yuan Gu (Συγγραφέας), Jingjing Huang (Συγγραφέας), Bin Zhan (Συγγραφέας), Xinping Zhu (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Public Library of Science (PLoS), 2016-09-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

BACKGROUND:Our previous studies showed that Trichinella spiralis paramyosin (TsPmy) is an immunomodulatory protein that inhibits complement C1q and C8/C9 to evade host complement attack. Vaccination with recombinant TsPmy protein induced protective immunity against T. spiralis larval challenge. Due...